What Do You Know About Valerophenone?

Feb. 02, 2023

Valerophenone cas no.1009-14-9, also known as 4-phenylbutan-2-one, is an organic compound with a sweet floral fragrance. It is a colorless liquid with a low boiling point and high vapor pressure.

Valerophenone is synthesized by the reaction of phenylacetaldehyde and acetone, using a palladium catalyst. This reaction is an example of the Hecke reaction, a chemical reaction involving the coupling of an olefin and an alkyne to form a new olefin.



Fragrance Industry

Valerophenone is used as a fragrance ingredient because of its sweet, floral fragrance. It is used in the manufacture of fragrances for perfumes, hygiene products and household products.

Flavoring Industry

Valerophenone is used as a flavoring agent to provide sweetness and floral aroma to food and beverage products.

Synthesis of Other Compounds

Valerophenone is used as a starting material in the synthesis of pharmaceuticals and other chemicals.

Organic Synthesis

Valerophenone is used as a base material for the synthesis of other organic compounds.


Valerophenone is used as a starting material or intermediate in chemical research and development.


The safety of valerophenone has been evaluated by different organizations, including the International Fragrance Association (IFRA) and the European Cosmetics Committee (EC). Based on these assessments, valerophenone is considered safe for use in perfumes and fragrances as long as it is used according to established guidelines. However, as with any chemical, exposure to high purity of valerophenone may cause eye, skin and respiratory irritation. In addition, Valerophenone's high vapor pressure means that it can easily evaporate into the air, potentially exposing people to its fumes. For this reason, care must be taken when handling valerophenone, and appropriate protective equipment must be used.

In conclusion, valerophenone is a versatile and important compound with a wide range of applications in the fragrance and flavor industry and in the synthesis of other chemicals. While it is considered safe to use when handled properly, it is important to be aware of its potential risks and to use appropriate protective equipment when working with it.

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