Pharmaceutical Intermediate
Dimethyl malonate is a reagent used in organic synthesis. It acts as a precursor for the synthesis of mono-substituted and di-substituted acetic acid, barbiturates, vitamin B1 and vitamin B6. It is used in the pharmaceutical industry to prepare pharmaceuticals like chloroquine and butazolidin.
Product Description
Organic synthetic intermediates.
A mixture of diethyl phthalate, carbon tetrachloride, and magnesium was added by drop to a mixture of diethyl malonate, carbon tetrachloride, and ethanol. The reaction was started by heating, and the temperature was controlled to make the reaction gentle. Then add anhydrous diethyl ether, heat for 1h, and add the diethyl ether solution of benzyl chloride (add slowly, not to make the reaction too intense). After the reaction, the oil layer was separated by cooling and adding water, and the diethyl phenyllemalonate was obtained by steaming diethyl ether under reduced pressure.
Product Name | bmk oil |
Density | 1.3±0.1 g/cm3 |
CAS NO | 20320-59-6 |
Molecular Formula | C13H14O5 |
Molecular Weight | 250.247 |
Appearance | yellow or red liquid |
Boiling Point | 327.8±42.0 °C at 760 mmHg |
Flash Point | 143.0±27.9 °C |
Exact Mass | 250.084122 |
PSA | 57.29000 |
LogP | 2.29 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.554 |
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Main products
Product name | CAS NO. |
BMK oil | 20320-59-6 |
PMK oil | 28578-16-7 |
1-Boc-4-Piperidone | 79099-07-3 |
1-Cbz-4-Piperidone | 19099-93-5 |
Tadalafil | 171596-29-5 |
2, 5-Dimethoxybenzaldehyde | 93-02-7 |
Valerophenone | 1009-14-9 |
Benzocaine | 94-09-7 |
2-Bromo-1-phenyl-1-pentanone | 49851-31-2 |
2-Bromo-4'-Methylpropiophenone | 1451-82-7 |
Tetracaine hcl | 136-47-0 |
Pyrrolidine | 123-75-1 |
2-Bromo-3-Methylpropiophenone | 1451-83-8 |
2-Iodo-1-P-Tolylpropan-1-One | 236117-38-7 |
Paracetamol | 103-90-2 |
Lidocaine hcl | 73-78-9 |
Levamisole hydrochloride | 16595-80-5 |
Tetramisole hydrochloride | 5086-74-8 |
Boric acid | 11113-50-1 |
CBD powder/ oil | 13956-29-1 |
Phenacetin | 62-44-2 |
Procaine hcl | 51-05-8 |
Lidocaine | 137-58-6 |
Tetracaine | 94-24-6 |
1, 4-Butanediol | 110-63-4 |
Isopropylbenzylamine | 102-97-6 |
Levamisole | 14769-73-4 |
4'-Methylpropiophenone | 5337-93-9 |
procaine | 59-46-1 |
N-Methylformamide | 123-39-7 |
Dimethocaine | 94-15-5 |
Packing&Shipping
1. Package: 25kg / 170kg / 230kg drum
2. Shipment: Shipping by Fedex, DHL, EMS or TNT; Shipping by Air or by Sea
Safe and Fast Delivery
1) Most items are in large stock, so the products can be sent out within 24 hours after payment confirmed, tracking number and packing details will be informed as soon as possible;
2) We can use special package like snacks, shampoo and others to pack products, it's very hidden and convenient;
3) Germany/ Netherlands/ Canada/ Australia warehouse stock which support self-pickup and fast delivery;
4) Customs pass rate ≥99%;
5) Secure and discreet shipment. various transportation methods for your choice,by sea, by air are all available.
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